The decision affects the indication of niacin extended-release (Niaspan, AbbVie) and fenofibric acid (Trilipix, AbbVie), as well as AbbVie's Advicor and Simcor, both of which combine niacin with a. Fenofibrate belongs to a group of drugs known as fibrates. It helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries). Common Questions and Answers about Fenofibrate vs niacin tricor I eat a lower fat diet, exercise by walking 40 minutes 5-6 times per week, don't smoke, control borderline hypertension with 5mg lisinopril daily, have a BMI of 30 but don't have enough self control to lose any weight. This study will evaluate the efficacy of diet and exercise (DE), with and without niacin and fenofibrate, in reducing the cardiovascular risk of patients with HIV lipodystrophy or dyslipidemia. Fenofibrate, sold under the brand name Tricor among others, is a medication of the fibrate class used to treat abnormal blood lipid levels. It is less preferred to statin medications as it does not appear to reduce the risk of heart disease or death. Objective: The aim of this study was to determine whether fenofibrate plus low-dose nicotinic acid adequately improves the lipoprotein profile in patients with diabetic dyslipidemia who are being treated with a statin. WASHINGTON -- In a move that signals the official end of an era for niacin and fibrate true believers, the FDA is rescinding its approval of niacin and fibrate combination products. There is no known interaction between Fenofibrate and Niacin in our records. However, an interaction may still exist. However, an interaction may still exist. Always consult your doctor before taking these medications together. Fenofibrate comes as a capsule, a delayed-release (long-acting) capsule, and a tablet to take by mouth. It is usually taken once a day. Some fenofibrate products (Fenoglide, Lipofen, and Lofibra) should be taken with a meal. Combination of Niacin and Fenofibrate with Lifestyle Changes Improves Dyslipidemia and Hypoadiponectinemia in HIV Patients on Antiretroviral Therapy: Results of “Heart Positive,” a Randomized, Controlled Trial.